Experimental Biomedical Research

Course Structure

1. Introduction to Brain and CNS
2. Overview Psychiatric Disorders Stress
3. Depression and the Brain
4. Biological bases of psychiatric disorders
5. Deep brain stimulation and brain disorders
6. Cortical stimulation and restorative functions
7. Overview neural pathologies, brain plasticity
8. Cognitive recovery after brain lesion
9. Neuroimaging correlates of functional recovery and plasticity
10. Cortical and spinal cord plasticity in motor recovery
11. Nervous system regeneration
12. Myocardial Infarction Models
13. Model systems for aging research and age-related diseases
14. Models of Metabolic Susceptibility to Obesity
15. Mouse Models of Human disease: a biotech perspective
16. Models for neuropsychiatric disorders
17. Stem cells and disease modeling:facts or science fiction
18. Human knock-outs: genetic defects in endocrinology and metabolism
19. Kidney models for nephrological disease
20. Introduction to Program and Course Unit
21. Concepts of Inflammation
22. Current concepts of cancer
23. Cancer research
24. Asbestosis: Foreign body reaction
25. Inflammation and tumourneogenesis
26. Concepts of nanomaterials in biomedicine
27. Concepts of immunotherapies
28. Concepts of cancer therapies
29. Concepts in Bacterial research
30. Concepts in antibiotics research
31. Concepts in viral research
32. Concepts in malaria research
33. Concepts in antimicrobial immune mechanisms
34. Evaluation and Feedback on unit, Mock exam
35. Fundamentals of optical microscopy and fluorescence imaging
36. Confocal Microscopy
37. Fluorescent probes
38. Koheler illumination and contrast methods
39. Digital image acquisition and processing
40. Live imaging
41. Emerging methods: light sheet microscopy
42. Research seminar 1: tdb
43. Emerging methods: superresolution microscopy
44. Research seminar 2: tdb
45. Make your own microscope
46. Confocal
47. Live imaging
48. TL microscopy
49. Image processing
50. Inferential statistics and experimental design
51. Introduction to Unit
52. Review article presented
53. Literature research
54. Referencing
55. Reference administration/EndNote
56. How to make a poster
57. How to write an original research article
58. How to write a thesis
59. How to write a research proposal
60. How to write a research grant application
61. How to chose the right methods?
62. Human Ethics
63. Animal Ethics
64. How to write an ethics application
65. Presentation of topic for review article
66. Feedback on how to make a good presentation
67. Editing
68. Evaluation and Feedback on unit
69. Screening for cognitive disorders in patients
70. EEG recording and analysis
71. Eye tracking in non-human primates
72. Motor skill learning in non-human primates
73. Interpreting self-evaluation forms in psychiatric patients
74. EEG signatures of psychiatric disorders
75. Dynamics of balance training
76. Introduction on the environment of Matlab
77. Variables : cells, double, string, numeric.
78. Vectors/Matrices: (Indexing, retrieving values,etc..)
79. Show basic useful functions in Matlab
80. Show logical operators
81. Creating scripts in Matlab
82. Show the if/else, loops (for, while)
83. Content provided by teacher during course
84. Recap Matlab I
85. Handling data
86. Plotting data
87. Measures of centrality and of dispersion
88. Pearson correlation/spearman correlation, P-values
89. Linear regression, parametric tests, non-parametric tests
90. Non-invasive brain stimulation techniques (TMS/tDCS/tACS)
91. Theoretical background and underlying physiological mechanisms
92. Applications in cognitive neuroscience and biological psychology
93. Hands-on experience
94. Introduction to Unit
95. Immune cells
96. Origine and Characteristics
97. T cells activation
98. Migration - Chemokines and Receptors
99. Summary and Discussion of labs 2-5
100. Phagocytes
101. Dendritic cells
102. Antigen processing and presentation
103. Summary and Discussion of labs 7 and 8
104. Cytokines
105. Cytotoxicity
106. Summary and discussion of labs 10 and 11
107. Student presentations
108. Evaluation of course and Mock Exam
109. T-cells
110. Types and function
111. How to perform echocardiography on small animal
112. How to induce myocardial infarction
113. How to assess myocardial infarct expansion
114. How to apply cell therapy for myocardial infarction
115. How to isolate bone marrow stem cell for cell therapy
116. How to induce atherosclerotic plaques in animal models
117. How to isolate and culture vascular wall cells and monocytes/macrophages
118. How to measure nitric oxide, oxidative stress in vitro, ex vivo and in vivo
119. How to analyze cardiovascular inflammations
120. How to study vascular aging and lifespan in animal models
121. How to monitor blood pressure and heart rate in vivo in animal models
122. Phenotypic expression of adiposity in population and gene-search studies
123. Recent advances in concepts about health risks related to body composition phenotypes
124. Assessment of human variability in energy expenditure, fuel oxidation and core temperature
125. Gender differences in metabolic susceptibility to obesity and cardiometabolic diseases
126. Compounds that stimulate thermogenesis and fat oxidation in obesity management
127. Targeting brown adipose tissue thermogenesis in human obesity and the metabolic syndrome
128. How to analyze renal function
129. How to determine and differentiate different types of proteinuria
130. Assessment of proteolytical activity in fluids
131. How to perform genotyping of knockout mouse models
132. How to induce acute/chronic kidney injury
133. Recognition of renal structures in kidney disease